+CAV2.3 expression is upregulated in the substantia nigra pars compacta of humans with Parkinson's disease

نویسندگان

چکیده

• Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) is responsible for motor symptoms Parkinson's disease. R-type calcium channels have been linked to selective vulnerability nigral an animal model Immunohistochemistry was used examine CAV2.3 expression human brains. In disease patients higher than those neighbouring ventral tegmental area and control might be therapeutic targets

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ژورنال

عنوان ژورنال: Brain disorders

سال: 2022

ISSN: ['2666-4593']

DOI: https://doi.org/10.1016/j.dscb.2022.100031